Dane -- who shot to fame amid six seasons on the hit ABC drama "Grey's Anatomy," where he played Dr. Mark Sloan, affectionately known as "McSteamy" -- said his symptoms began over one year ago, when he began to experience weakness in his right hand.

Eric Dane announced his ALS diagnosis in April 2025. Here's everything Eric Dane has said about his ALS diagnosis and his health since he shared the news.

An emotional Eric Dane is sharing about his ALS journey in his first TV interview since he publicly announced his diagnosis, telling ABC News’ Diane Sawyer that the disease does not represent the end of his story.