Iran and the United States will hold talks Saturday in Rome, their second round of negotiations over Tehran’s rapidly advancing nuclear program

As Iran and the United States prepare for a new round of indirect nuclear talks in Rome, shifting US positions, sidelined European powers, and military buildups are complicating the path to diplomacy.

The United States and Iran are due to hold their second round of nuclear talks on Saturday, as what both sides are looking for in a deal begins to take shape.