Discover the latest Detroit Lions Week 1 odds, betting lines and expert picks for the 2025 NFL season opener. Lions vs.

However, if you go through the point spreads for each week — yes, those are already out; never discount gamblers' eagerness — the Texans are favored in just nine games this season.

2025 NFL futures: Aggregate point spreads provide another component for analyzing teams, odds SportsLine has crafted a season-long NFL spread formula that can serve as a data point for team rankings.

It's Browns vs. Bengals in the "Battle of Ohio" right off the bat in 2025. Our expert give his best bets for that game, as ...

Until it's done, we can't be certain. The Steelers are a 3-point road favorite for that Week 1 game at BetMGM, and that would change dramatically if Mason Rudolph is their quarterback.