Context Enhanced platelet inhibition by clopidogrel decreases the risk of ischemic events but carries a risk for a concomitant increase in bleeding. Objectives To compare the efficacy and safety of ...

A series of optically active 2-hydroxytetrahydrothienopyridine derivatives were designed and synthesized as prodrugs of clopidogrel thiolactone in order to overcome ...

What is the influence of proton pump inhibitors, specifically omeprazole, on the antiplatelet efficacy of clopidogrel?

This important discussion among experts who are engaged with clopidrogrel resistance cover personalized medicine and what to do until we get there.

Background The extent of clopidogrel-mediated platelet inhibition varies considerably from one person to the next. Numerous studies have shown that low responders have significantly more adverse ...