Clopidogrel, a thienopyridine derivative, was shown to reduce the relative risk of ischemic stroke, myocardial infarction, or death from vascular causes in patients with prior cardiovascular ...

Treating coronary artery disease patients with monotherapy using clopidogrel or ticagrelor was associated with lower rates of ...

Current evidence seems to indicate that due to individual variability in response to clopidogrel, as many as 30% of patients on maintenance clopidogrel (75 mg/day) may show elevated platelet ...

As clopidogrel is now recommended for all ACS patients, this could have an important effect on the statin market. (Lau WC et al. Circulation 2002, published online before print November 25, News ...

The efficacy of clopidogrel in combination with acetylsalicylic acid (ASA) therapy has been clearly established in well-designed randomized controlled trials that have shown a reduction in recurrent ...

Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical significance of this drug interaction is unknown. Methods: We conducted a ...

Clopidogrel (Plavix) monotherapy was superior to aspirin monotherapy for long-term post-stent maintenance in patients who had percutaneous coronary intervention (PCI), according to results of the ...

Clopidogrel, he added, is a more-potent antiplatelet agent, although there is the worry that its use might lead to more bleeding. However, the most common type of bleeding that clinicians encounter is ...

Taking Another Look at Clopidogrel? Based on this study and others published in recent years indicating perhaps a blunting of the benefits of more-potent P2Y12 inhibitors in contemporary, real-world ...

Dual antiplatelet therapy with aspirin and clopidogrel is currently the standard of care to prevent stent thrombosis after percutaneous coronary intervention with bare metal stent or drug-eluting ...

As compared with clopidogrel administered immediately before or after PCI, intravenous ADP-receptor blockade with cangrelor significantly reduced the rate of periprocedural complications of PCI, ...

Clopidogrel is one of the most important drugs utilized for secondary prevention of ischemic events in patients with ACS who undergo PCI. Therefore, numerous investigations have been conducted to ...