Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season ...

NFL.com's Coral Smith breaks down four things to watch for when the San Francisco 49ers host the Detroit Lions on Monday night.

While the San Francisco 49ers have officially been eliminated from the playoffs and have nothing left to play for but pride ...

With each passing game, the NFL playoff picture rounds further into shape. Here's how the NFL playoff bracket looks after ...

After a miserable run with my NFL picks, it's been two straight weeks of solid picking for me. I went 9-6-1 against the ...

His absence Monday further depletes an injury-riddled 49ers offensive line that may need to turn to recently signed veteran Charlie Heck at left tackle on Monday. Things will be even more dire for San ...

Spencer Burford officially has been ruled out of San Francisco's Week 17 game against the Detroit Lions on Monday night at ...

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week’s game with a hamstring injury, does not have an injury designation for the game against the ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

When do the Detroit Lions play today? The Lions are off Sunday and will play the San Francisco 49ers on Monday Night Football ...

The NFL Week 17 schedule ends with a rematch of the 2023 NFC Championship game when the Detroit Lions travel to the West ...

As the 49ers look to play spoiler against the Lions on Monday Night Football, RB Isaac Guerendo got a positive injury update.