Jan 16, 2025 · Regulatory T cells (Tregs) are increasingly being recognized for their role in promoting tissue repair. In this issue of the JCI, Chen et al. found that Tregs at the site of bone …

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Dec 2, 2024 · In this issue of the JCI, two reports (10, 11) define how distinct mechanisms, induced by RT, restrain STING signaling and can be blocked to amplify the immune-engaging …

Jan 16, 2024 · Over several decades the JCI has published key advances in our understanding of glucagon-like peptide 1 (GLP-1) biology. The first incretin peptide characterized in the 1970s, …

The JCI was founded in 1924 and is published by the American Society for Clinical Investigation (ASCI), a nonprofit honor organization of physician-scientists established in 1908. Impact …

Nov 26, 2024 · Find articles by Fu, Z. in: JCI | PubMed | Google Scholar 1 Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha, China. 2 …

Dec 6, 2024 · Systemic sclerosis (SSc) is characterized by immune system failure, vascular insult, autoimmunity, and tissue fibrosis. TGF-β is a crucial mediator of persistent myofibroblast …

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Nov 26, 2024 · However, there were no differences in CD31-positive ECs or αSMA-positive arterioles between the LysM-Cre +/– Drp1 +/+ and LysM-Cre –/– Drp1 fl/fl WT groups …